Sample Size Calculations

During the planning stages of a clinical study, SCiAN will work with you to establish the hypotheses of interest that reflect the study objectives under the study design.  Based on the hypotheses, SCiAN will:

  • Determine the number of subjects needed to detect a clinically meaningful difference at a required level of power
  • Discuss the trade-off in power should budget considerations be a factor determining the number of subjects.

If prior knowledge regarding the endpoints of interest is limited or inaccurate, we can help design your study to allow for interim analyses and sample size recalculation to ensure that your study is not under/over powered.